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Editor,
The Journal of Integrative Medicine
Formerly, Associate Professor of Pathology (adj.), College
of Physicians
and Surgeons of Columbia University, NY
Formerly, President of Staff and Chief Pathologist,
Holy Name Hospital, Teaneck, NJ
Fellow, Royal
College of Surgeons of England -
Diplomate,
American Board of Anatomic and Clinical Pathology
Diplomate, American Boards of Environmental Medicine
Past President Capital University of Integrative
Medicine |
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The Aging Healthfully Virtual Library
- The Works of Majid Ali, M.D.
__________________________________________________________________
Oxidative Theory of Cancer
From The Book RDA: Rats, Drugs and
Assumptions
PART 3
A CANCER CELL BREATHES OXIDATIVE FIRES
Cancer cells---like the mythical Chinese dragons---breathe oxidative fires. They produce
prodigious amounts of hydrogen peroxide---one to two hundred times as much as is produced
in non-cancer cells. Indeed, even immune cells at the height of their activity during
their attack on microbes do not come close to cancer cells as regards the amounts of
hydrogen peroxide produces.
Cancer cells---like the Greek crabs after which they are named---send out tiny projections
that are in reality tentacles of oxidative coals, ready to light up the plasma proteins of
oxidative flames. These projections are made up of tiny bits of the cell membrane as well
as the cell soup of cancer cells. Frequently these tentacles get pinched off, form
complexes with clotting proteins such as Factor VII, and ignite the oxidative flames that
engulf other clotting proteins such as Factor IX and X. (Factors VII, IX, and X are among
the substances that are essential for normal blood clotting.) The end result of these
reactions is that the cancer cells get surrounded by fibrin nets that protect them from
natural killer and other immune cells that normally search and destroy errant cells
including cancer cells. These reactions also break contact of cancer cells with other
malignant cells that surround them. Thus, cancer cells are freed and begin to travel
to other parts if the body, looking for new sites to seed and flourish.
Each cancer cell floating free in the blood, lymph and tissues carries simmering oxidative
coals, ready to burst into oxidative flames at the slightest provocation, thereby
triggering further oxidative reactions.
Simple molecules
self-assemble into amino acids; amino acids self-assemble into functioning proteins
I
have considerable difficulty accepting drug medicine's prevailing gene theory of cancer
and the attendant notions of the irreversibility of cancer. There are several fundamental
observations in chemistry that challenge the assumption made in gene theory.
Do genes really control everything? In their famous 1953 experiment,
Stanley Miller and Harold Urey of the University of Chicago, subjected simple molecules
such as ammonia, methane, hydrogen and water in a flask to repeated cycles of heating,
electrification and cooling---conditions that are thought to have existed when life began
on planet Earth. The experiment produced a crimson-colored primordial soup, rich in amino
acids. Amino acids, of course, are the building blocks of protein, including enzymes.
In subsequent years, origin-of-life research has been focused on the
fundamental chemical mechanisms of prebiological molecules. Notable among these studies
are those of Sidney Fox who clearly demonstrate that under primordial conditions, amino
acids could self-assemble into proteins---without the intervention of genes. The next
important step was to demonstrate whether or not proteins so formed could assemble
themselves into tiny protein microspheres---the precursors of cells as we know them today.
Experiments clearly showed that this assemblage does occur.
If the
reactions within a sphere help make macromolecules, then we're talking about a cage in
which thermal proteins could help build nucleic acids like RNA or DNA. Perhaps thermal
proteins can also help synthesize true proteins...through this type of mechanism, cellular
evolution could have arisen from microspheres.
Biologist Aristotle Pappelis
Quotes in Science News 146:59,1994
I
include these brief comments about the origin-of-life research to support my view that
molecules have their own minds---their own sense of the natural order of things. Simple
molecules, such as ammonia and water, larger molecules, such as amino acids, and complex
molecules such as proteins (including) enzymes, can assemble and disassemble themselves
without any organizing influence of genes. Such observations challenge the notions of
irreversibility of cancer cells of drug medicine.
Where does cancer begin? What are the initial energetic-molecular
events that turn a healthy cell into a cancer cell? How does a cancer cell go into
nonoxygen-utilizing mode---become an oxyphobe? How does it begin to produce prodigious
amounts of hydrogen peroxide? How does it accumulate electrons on its surface and become
strongly negatively charged?
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