The Darwin Trilogy The Principles and Practice of Integrative Medicine Majid Ali, M.D. Available Now

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Formerly, Associate Professor of Pathology (adj.), College of Physicians
and Surgeons of Columbia University, NY
Formerly, President of Staff and Chief Pathologist, Holy Name Hospital, Teaneck, NJ

Fellow, Royal College of Surgeons of England - Diplomate,
American Board of Anatomic and Clinical Pathology
Diplomate, American Boards of Environmental Medicine
President Capital University of Integrative Medicine

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DHEA, dehydroepiandrosterone, is a primary adrenal hormone which serves as one of the body's major anti-aging hormones. In contrast to steroids that depress our antioxidant and immune defense systems, DHEA supports such defenses. (I will let you in on a secret: Holistic physicians prescribe DHEA liberally for their family members, and most of them take it themselves for enhancement of their general antioxidant and immune defenses.) I consider this an excellent agent for restoring the damaged antioxidant and immune defenses of chronic stress sufferers. Indeed, it is a very rare patient who does not report beneficial results within weeks or months of taking it.

I frequently use DHEA in a daily dose of 50 mg for the first three months and then reduce the dose to 50 mg on alternate days. In most cases, such therapy may be discontinued within several months when normal enzyme functions—and energy levels—are restored.

1. DHEA has many established beneficial effects on the immune system.

2. Stress states are associated with suppression of several immune functions; DHEA prevents that.

3. Blood DHEA levels are usually reduced in chronic fatigue sufferers, and replacement therapy with DHEA improves the overall energy level and reduces many associated symptoms.

4. DHEA opposes the physiological effects of cortisone in several animal models.

5. DHEA levels drop in serious infections, including AIDS, indicating progression of disease, and the levels rise during recovery.

6. DHEA protects immune cells against acute lethal viral infections (including viral encephalitis).

7. DHEA regulates many immune cell functions and the production of hormone-like mediators called lymphokines. It helps generate many desirable molecules (such as IL-2) and prevents the excessive production of some undesirable ones, such as interleukin 4 and 5 and gamma interferon that can impair our immune defenses. A role of DHEA in the cause of systemic lupus—an autoimmune disorder—has been suggested.


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This information is provided only to provide information, it is never, ever to be used as a self help guideline. Always consult your own health care provider for information or questions on your health! Throughout this website, statements are made pertaining to the properties and/or functions of nutritional supplements. These statements about nutritional supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure or prevent any disease

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