Alzheimers Disease

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Who is
Majid Ali, M.D.
► Dr. Ali's CV

Majid Ali is a pioneer who is changing the face of medicine with his innovative and spirited approach.

His credentials are impeccable Complementary Medicine Journal

"I stand in awe of Ali's superb scientific knowledge, his insights into the nature of the the healing process and his ability to explain hard science."

Aubrey Worrell, MD
Past President, the American Academy of
Environmental Medicine

Majid Ali, M.D.
Editor, The Journal of Integrative Medicine

Formerly, Associate Professor of Pathology (adj.), College of Physicians and Surgeons of Columbia University, NY

Formerly, President of Staff and
Chief Pathologist, Holy Name Hospital, Teaneck, NJ

Fellow, Royal College of Surgeons of England - Diplomate,

American Board of Anatomic and Clinical Pathology

Diplomate, American Boards of Environmental Medicine

Past President Capital University of Integrative Medicine

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OXYGEN, GENES, MEMORY, AND ALZHEIMER’S DISEASE
The incidence of Alzheimer’s disease (AD)—a problem of shrinking brain that robs the victim of memory and mentation—is rising worldwide at frightening rates. About 5.5 million Americans suffer from this dreaded disorder. According to the Alzheimer’s Association, one in eight people over age 65 have the disease. The annual cost to the nation is $183 billion. These figures, as disturbing as they are, do not adequately reveal the devastating problems of the dysfunction and death of brain cells. I am equally concerned about the problems of memory deficit among the young that is spreading like an epidemic.

Toxicities of foods, environment, and thoughts (disappointments, chronic anger, and mental health issues) impede or block the energetic, detergent, and developmental functions of oxygen. Dysfunctional oxygen metabolism (dysox) so produced causes injury and loss of brain cells and is the beginning of inflammation, deposition of amyloid proteins, and plaques formation that are the hallmarks of AD. This is the scientific basis of my Oxygen Model of Alzheimer’s Disease.

Oxygen Model of Alzheimer’s Disease Validated

Medical models are proposed to reduce complexities in biology to workable simplicities and to predict clinical characteristics of diseases. In the context of genetics, The Oxygen Model of Alzheimer’s Disease predicts that the genes to be linked with the disease will be primarily involved with oxystatic, inflammatory, and detoxification pathways in the brain. This prediction was proven correct in April 2011 with the publications of two large studies in the journal, Nature Genetics. A gene analysis of more than 50,000 people in the United States and Europe doubled the number of genes—from five to ten— that increase the risk of Alzheimer’s disease. All ten are involved with inflammation and cholesterol metabolism. Cholesterol, of course is an antioxidant and, like other antioxidants in physiologic ranges in human biology, serves anti-inflammatory roles and favorably influences molecular traffic across cell membranes.

The Oxygen Models of Memory Disorders and Alzheimer’s Disease

I put forth the oxygen models of memory disorders (dementia of various types and memory in the young) and Alzheimer’s disease to underscore the commonality of underlying energetic-molecular basis (add “and”???)a range of clinical, pathologic, and experimental observation concerning mental function. These unifying models meet the two essential characteristics of medical models mentioned above. In companion articles, I address problems of early and reversible memory loss in young people, memory loss associated with various forms of dementia, and AD to underscore the commonality of insults to brain cells and cellular dysfunction. Specifically, these models:

1. Explains the scientific basis of memory lapses due to deranged oxygen signaling;
2. Show how toxicities of foods, environments, and thoughts cause the loss of brain cells and plaques associated with clinical features of AD;
3. Reveal the mechanisms by which various direct and indirect oxygen therapies (including bowel and liver detox) work;
4. Compel clinicians to focus on all threats to oxygen homeostasis (balance) to restore the health of brain cells and mental functions;
5. Shed light on how all bodily functions improve when oxygen therapies are employed to improve the circulation and oxygen supply to the brain; and
6. Provide explanations of mechanisms by which time-honored natural remedies work to prevent or reduce the problems of memory and mentation.

Genetic Risks of Alzheimer’s

The main gene incriminated in AD is the gene for a protein called APO-E, which was discovered in 1995. It increases the risk for the disease by 400 percent if one copy is inherited from one parent and by 1,000 percent if from both parents. APO-E is involved with the metabolism of cholesterol. However, the genetic risk of a disease does not mean the presence of that disease. It is well established that genes respond to environmental changes (including the matters of foods and stress)—epigenomics, the field dealing with the phenomena is mushrooming—and we do not how many more genes carrying such risks will be discovered in the future.

In contrast, the newly discovered genes increase risk by about 10 to 15 percent. Researchers already believe it will not be reliable to use them to decide if a person is likely to develop Alzheimer’s. So, despite the front page story in The New York Times of April 4, 2011, the great jubilation about the recent discoveries do not signify much for people with AD.

While the new discoveries will undoubtedly open new venues for research in AD, they also underscore the importance of diligent and thoughtful examination of the issues of nutrition, environment, and stress that increase the risk of AD.

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E- BOOKS

Oxygen
and Aging,
Majid Ali, M.D.
$9.95 490 pages

Kindle	IPAD/NOOK	PDF
RDA Rats, Drugs and Assumptions ISBN 1-879131-07-2 A book that challenges most of the cherished assumptions of drug medicine. It lays bare many of the deceptions in medical statistics - most of them intended, it seems. It shows how results of valid medical research are deliberately distorted to promote long-term use of drugs of dubious value. It exposes the deep prejudice of practitioners of drug medicine against natural, non-toxic drug therapies. This book clearly delineates the scientific basis of energetic-molecular events that cause disease, and shows how accelerated oxidative injury to human enzyme systems - comprised of energy, detoxification and digestive enzymes - is the cause of all disease processes. Furthermore, it describes how oxidative enzyme injury leads to disruptions of the bowel, blood and other body organ ecosystems.
PDF $6.95	NOOK/IPAD $6.95	KINDLE $6.95
The Ghoraa and Limbic Exercise ISBN 1-879131-02-1 335 pages Trade paperback This book is about some ancient universal concepts that can be applied in everyday life. Ali's outstanding book combines the "limbic" language of silence with physical exercise. Read and try it, you'll like it! Doris Rapp, M.D., Author, Is This Your Child? Can physical exercise provide a deeply personal, treasured retreat from the relentless chatter of the thinking mind? Learn how slow, sustained exercise can be combined with "limbic language" to achieve higher levels of health and spiritual awareness. Exercises specifically designed for specific disorders Reviews "At last a book that helps you discover the exhilaration of motion for motion's sake." Robert C. Atkins, M.D., Author, Health Revolution
PDF $6.95	NOOK/IPAD $6.95	KINDLE $6.95
What Do Lions Know About Stress ISBN 1-879131-10-2 Trade Paperback 550 pages "Our leaders in business and politics need to learn about stress - and Ali's lions have some valuable lessons for them! Professor Julio Sotelo, Cornell University Medical College, New York A Different View of Stress A physician does his most worthy work when he participates in his patient's suffering. In participating in their suffering, my patients with severe, chronic stress have given me two insights. First, the common notion of stress being fight-or-flight response to a demand for change is so inadequate as to be clinically irrelevant. Second, spirituality makes psychology irrelevant. In this volume, I include many true-to-life stories of my patients and describe the energetic-molecular basis of their suffering. I relate how long hours of listening to them led me to conclude that the popular notion of mind-over-body healing is a cruel joke, and, in essence, pours salt on their wounds. I also recognized that the prevailing practice of searching for relief of the agony of the present through 'working out the problems of the past' is little more than a cortical trap-the mind endlessly recycles past pain or recycles feared, future misery. Psychology, by and large, keeps us incarcerated in obsolete models of disease and sufferings. Spirituality set us free.
LIONS PDF $6.95	NOOK/IPAD $6.95	KINDLE $6.95
The Butterfly and Life Span Nutrition ISBN 1-879131-01-3 419 pages, trade paperback A compelling book that calls dieting a myth and gives original and innovative solutions to the problem of nutrition, health, and obesity. Geared to repeat dieters who have dieted their way into poor health. This book also highlights Dr. Ali's theory on oxidation as the cause of aging! Chapter include On the Nature of Obesity; Stress, Obesity and the Language of Silence. Why Dieting Does Not Work; The Catabolic Maladaptation; Life Span Food Choices; On Limbic Eating!
Butterfly PDF $6.95	BUTTERFLY NOOK/IPAD $6.95	BUTTERFLY KINDLE $6.95
The Dysox Model of Cancer Majid Ali, M.D. $9.95 472 pages
Kindle	IPAD/NOOK	PDF
The Oxygen Protocol for the Treatment of Cancer Majid Ali, M.D. $9.95 400 pages Chapters in theses works include: 1. Restoring Bowel Health 2. Restoring Liver Health 3. Restoring Blood Health 4. Alkalizing therapies 5. Enzyme therapies 6. Oxygen therapies 7. Limbic breathing 8. Sleep 9. Spice Medicine and much more
Kindle	IPAD/NOOK	PDF
E- BOOK $9.95 Instant Download PDF VERSION ONLY! Dr. Ali presents his plan for reversing Diabetes. In cases when diabetes cannot be reversed due to complete insulin depletion, this book offers valuable information on avoiding the complications of diabetes.

The Canary and Chronic Fatigue Chronic Fatigue sufferers are human canaries--unique people who tolerate poorly the biologic oxidative stressors of the late 20th century. They are genetically predisposed to injury and their energy and detoxification enzymes by agents in their internal and external environments. Their molecular defenses are damaged by undiagnosed and unmanaged allergies, chemical sensitivities, environmental pollutants, microbes, sugar-insulin-adrenaline roller coasters, stress and hostility of sped up lives. Under their skin, they carry oxidative storms--the Fourth of July chemistry. This book offers information and guidance about nondrug therapies that do work for the fatigue sufferer as well as the professional.
E-Book price $9.95 PDF VERSION ONLY
Integrative Protocols of Integrative Medicine Includes Dr. Ali's IV and IM formulations
E-Book price $35 PDF VERSION ONLY

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