Hyperchlorhydria, gastric acid, bloating, gas, stomach problems

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Who is
Majid Ali, M.D.
► Dr. Ali's CV

Majid Ali is a pioneer who is changing the face of medicine with his innovative and spirited approach.

His credentials are impeccable Complementary Medicine Journal

"I stand in awe of Ali's superb scientific knowledge, his insights into the nature of the the healing process and his ability to explain hard science."

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Past President, the American Academy of
Environmental Medicine

Majid Ali, M.D.
Editor, The Journal of Integrative Medicine

Formerly, Associate Professor of Pathology (adj.), College of Physicians and Surgeons of Columbia University, NY

Formerly, President of Staff and
Chief Pathologist, Holy Name Hospital, Teaneck, NJ

Fellow, Royal College of Surgeons of England - Diplomate,

American Board of Anatomic and Clinical Pathology

Diplomate, American Boards of Environmental Medicine

Past President Capital University of Integrative Medicine

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Originally published in 1993

ALTERED STATES OF
GASTRIC ECOLOGY
Majid Ali, M.D.

Altered gastric ecology is one of the dominant chronic disorders of our time. Most — though not all — chronic fatiguers develop problems of indigestion and upper abdominal discomfort after variable periods of fatigue.

A fundamental difference in concept between the altered states of bowel ecology and gastric ecology in the past was that the former was predominantly a "bio-ecosystem" while the latter was essentially a "chemical ecosystem." This concept is rapidly changing; the most visible villain, of course, is the microbe Helicobacter pylori. I have a sense that we will encounter other microbes colonizing the gastric ecosystem in the future as the use of antacids, histamine receptor blockers, nonsteroidal drugs for joint disorders, steroids and other drugs becomes more pervasive.

Gastric acidity — secretion of hydrochloric acid by the stomach lining — is essential for the digestive efficiency of pepsin and for the absorption of minerals such as iron. It is one of the primary host defenses against viral and bacterial infections and against parasitic infestations. Pepsin digestion (and ongoing salivary amylase and other enzyme functions) within the stomach lumen is required for preparing food for digestive-absorptive functions in the small bowel. Normal gastric motility preserves the gastric reservoir function without which undigested foods would readily enter the bowel. A detailed discussion of the patho-physiology of the stomach and derangement of gastric function that leads to gastritis-peptic ulcer continuum as well as to the hypochlorhydria-malabsorption spectrum is outside the scope of this monograph. However, symptom-complexes induced by an altered gastric ecology have become pandemic. Further, bowel ecology disorders frequently cannot be reversed without carefully addressing gastric ecology.

Enzymes are proteins, and are easily injured by accelerated oxidative injury — the root of chronic fatigue. The enzymes of the stomach and intestines are no exception to this. I cite two examples of enzymes that are vulnerable to oxidative injury: H+,K+-ATPase and rhodanese. One type of cell in the stomach lining (parietal cells) in the gastric mucosa secretes hydrochloric acid by a process involving oxidative phosphorylation. This is one of the most astounding phenomena in nature: These cells secrete hydrogen ions at a concentration of about 3 million times that found in blood. So intense is the process that one bicarbonate ion released into the blood as a reciprocal event for secretion of each hydrogen ion causes the alkaline tide in the blood Ph. A key enzyme involved in this proton pump mechanism is the specific enzyme, hydrogen-potassium adenosine triphosphatase (H+,K+-ATPase). Reciprocal bicarbonate release into the blood is mediated by parietal cell carbonic anhydrase.

Rhodanese is a sulfur-transferring enzyme in the surface of cells lining the intestinal surface. It takes cyanide from cyanogenic foods and combines it with thiosulfates to make thiocyanate—a molecule that is necessary for production of acid in the stomach. It is likely that many digestive symptoms in chronic fatigue—especially stomach fullness after small meals—are due to oxidative injury to rhodanese. Thiocyanates are also required for iodine storage as well as for optimal function of ATPase—another essential energy enzyme.

HYPERCHLORHYDRIA AND HYPOCHLORHYDRIA
Hyperchlorhydria — too much acidity — is a gastric maladaptive response to the changes in gastric ecology in chronic fatiguers. Such persons are often given massive quantities of antacids for "regulating" abnormal patterns of gastric acidity — a sad reflection on our capacity for understanding the true nature of these problems. Antacids suppress gastric acidity when it is needed and promote it (through rebound phenomenon) when it is unnecessary. Antacids are a common source of aluminum overload and toxicity. The worst side-effect of antacids, in my judgment, is this: Antacids suppress the symptoms that draw our attention to the underlying abnormalities of the gastric structure and function.

Hypochlorhydria — not enough gastric acid — is much more common among human canaries. Gastric acidity normally declines as we age. Hypochlorhydria is almost a constant feature of atrophic gastritis in the elderly. It is seen with high frequency in patients with recurrent episodes of chronic gastritis. Studies on healthy college students have shown hypochlorhydria to occur following acute viral infections in one-third to one half of volunteers. Hypochlorhydria occurring as a consequence of acute viral infections in otherwise healthy subjects can be expected to resolve spontaneously within a period of a few weeks.

For suspected or documented gastric hypoacidity, my own clinical preference is to avoid the use of acid-containing products such as betaine hydrochloride. Such products often carry the risk of inducing excessive acidity. The use of herbal digestives is much more desirable. Patients must be prepared for a slow restorative approach, as is done for other patients managed with nondrug management protocols of molecular medicine. Digestive enzymes administered with or soon after meals significantly expedite restoration of gastric ecology.

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E- BOOKS

Oxygen
and Aging,
Majid Ali, M.D.
$9.95 490 pages

Kindle	IPAD/NOOK	PDF
RDA Rats, Drugs and Assumptions ISBN 1-879131-07-2 A book that challenges most of the cherished assumptions of drug medicine. It lays bare many of the deceptions in medical statistics - most of them intended, it seems. It shows how results of valid medical research are deliberately distorted to promote long-term use of drugs of dubious value. It exposes the deep prejudice of practitioners of drug medicine against natural, non-toxic drug therapies. This book clearly delineates the scientific basis of energetic-molecular events that cause disease, and shows how accelerated oxidative injury to human enzyme systems - comprised of energy, detoxification and digestive enzymes - is the cause of all disease processes. Furthermore, it describes how oxidative enzyme injury leads to disruptions of the bowel, blood and other body organ ecosystems.
PDF $6.95	NOOK/IPAD $6.95	KINDLE $6.95
The Ghoraa and Limbic Exercise ISBN 1-879131-02-1 335 pages Trade paperback This book is about some ancient universal concepts that can be applied in everyday life. Ali's outstanding book combines the "limbic" language of silence with physical exercise. Read and try it, you'll like it! Doris Rapp, M.D., Author, Is This Your Child? Can physical exercise provide a deeply personal, treasured retreat from the relentless chatter of the thinking mind? Learn how slow, sustained exercise can be combined with "limbic language" to achieve higher levels of health and spiritual awareness. Exercises specifically designed for specific disorders Reviews "At last a book that helps you discover the exhilaration of motion for motion's sake." Robert C. Atkins, M.D., Author, Health Revolution
PDF $6.95	NOOK/IPAD $6.95	KINDLE $6.95
What Do Lions Know About Stress ISBN 1-879131-10-2 Trade Paperback 550 pages "Our leaders in business and politics need to learn about stress - and Ali's lions have some valuable lessons for them! Professor Julio Sotelo, Cornell University Medical College, New York A Different View of Stress A physician does his most worthy work when he participates in his patient's suffering. In participating in their suffering, my patients with severe, chronic stress have given me two insights. First, the common notion of stress being fight-or-flight response to a demand for change is so inadequate as to be clinically irrelevant. Second, spirituality makes psychology irrelevant. In this volume, I include many true-to-life stories of my patients and describe the energetic-molecular basis of their suffering. I relate how long hours of listening to them led me to conclude that the popular notion of mind-over-body healing is a cruel joke, and, in essence, pours salt on their wounds. I also recognized that the prevailing practice of searching for relief of the agony of the present through 'working out the problems of the past' is little more than a cortical trap-the mind endlessly recycles past pain or recycles feared, future misery. Psychology, by and large, keeps us incarcerated in obsolete models of disease and sufferings. Spirituality set us free.
LIONS PDF $6.95	NOOK/IPAD $6.95	KINDLE $6.95
The Butterfly and Life Span Nutrition ISBN 1-879131-01-3 419 pages, trade paperback A compelling book that calls dieting a myth and gives original and innovative solutions to the problem of nutrition, health, and obesity. Geared to repeat dieters who have dieted their way into poor health. This book also highlights Dr. Ali's theory on oxidation as the cause of aging! Chapter include On the Nature of Obesity; Stress, Obesity and the Language of Silence. Why Dieting Does Not Work; The Catabolic Maladaptation; Life Span Food Choices; On Limbic Eating!
Butterfly PDF $6.95	BUTTERFLY NOOK/IPAD $6.95	BUTTERFLY KINDLE $6.95
The Dysox Model of Cancer Majid Ali, M.D. $9.95 472 pages
Kindle	IPAD/NOOK	PDF
The Oxygen Protocol for the Treatment of Cancer Majid Ali, M.D. $9.95 400 pages Chapters in theses works include: 1. Restoring Bowel Health 2. Restoring Liver Health 3. Restoring Blood Health 4. Alkalizing therapies 5. Enzyme therapies 6. Oxygen therapies 7. Limbic breathing 8. Sleep 9. Spice Medicine and much more
Kindle	IPAD/NOOK	PDF
E- BOOK $9.95 Instant Download PDF VERSION ONLY! Dr. Ali presents his plan for reversing Diabetes. In cases when diabetes cannot be reversed due to complete insulin depletion, this book offers valuable information on avoiding the complications of diabetes.

The Canary and Chronic Fatigue Chronic Fatigue sufferers are human canaries--unique people who tolerate poorly the biologic oxidative stressors of the late 20th century. They are genetically predisposed to injury and their energy and detoxification enzymes by agents in their internal and external environments. Their molecular defenses are damaged by undiagnosed and unmanaged allergies, chemical sensitivities, environmental pollutants, microbes, sugar-insulin-adrenaline roller coasters, stress and hostility of sped up lives. Under their skin, they carry oxidative storms--the Fourth of July chemistry. This book offers information and guidance about nondrug therapies that do work for the fatigue sufferer as well as the professional.
E-Book price $9.95 PDF VERSION ONLY
Integrative Protocols of Integrative Medicine Includes Dr. Ali's IV and IM formulations
E-Book price $35 PDF VERSION ONLY

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